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This Concept Map, created with IHMC CmapTools, has information related to: Week 5, P-glycoprotein system Increases drug toxicity (inhibits elimination) Warfarin, Warfarin Enhances Anti-coagulatory effect, CYP2C9 interact to enhance Anti-coagulation, None cost? Pepcid: $0.28/ tablet, Arrhythmia Treated with Amiodarone, Zantac (Ranitidine) side effects None, 62 y/o female Week 0 Symptom 1 Patient has Blood Clot, Amiodarone Inhibits P-glycoprotein system, Heart burn treatment options Prevacid (Lansoprazole), Overall enhancement Enhances Coagulatory effect, None cost? Zantac: $3.25/tablet, St. Johns Wart Enhances CYP3A4, Side-effects 1-3 day inhibition of CYP2C9, St. Johns Wart Can cause Arrhythmia, Amiodarone Inhibits CYP1A2, 62 y/o female Week 0 Symptom 2 Heart burn, Tagamet (Cimetadine) inhibits CYP450 3A4, Zantac: $3.25/tablet Therapy for Symptom 2 No side-effects, Side-effects Affects 62 y/o female Week 1, Heart burn treatment options Zantac (Ranitidine)